Contacting the AlphaScrip Pharmacy Network

AlphaScrip provides pharmacy toll-free support in the event a pharmacist has a question about processing a claim.

Toll-Free Support


Help Desk Hours

Monday – Friday 8:00 am – 11:00 pm EST
Saturday 8:30 am – 10:00 pm EST
Sunday 9:00 am – 5:00 pm EST

AlphaScrip is an active member of the NCPDP (National Council of Prescription Drug Programs) participating in issues related to sample and prescription discount as well as related claim processing standards.


Pharmacies can also submit their inquiry below. For all program related questions including client support questions, please contact us on 1-800-664-6864.

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